| ncRNA name | hsa-miR-125b-5p |
| ncRNA Category | miRNA |
| Disease name | diabetic retinopathy (DR) |
| Species | Homo sapiens |
| Tissues/Cell_line | human retinal endothelial cells (HRECs), human RPE cell line ARPE-19 |
| Methods | MTS assay, transfection, qRT-PCR, Western blot |
| Expression pattern | down-regulated |
| Functional description | In this study, we confirmed that miR-125b-5p was expressed at low levels in both HRECs and ARPE-19 cells under hyperglycemia exposure and in the DM retina. Therefore, modulation of miR-125b-5p in early DR might exert beneficial effects with regard to slowing DR progression and DR-associated impairment. |
| PubMed ID | 28706953 |
| Year | 2017 |
| Title | Differentially Expressed MicroRNAs in the Development of Early Diabetic Retinopathy. |
| Drug-related ncRNA | NO |
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